Spectrophotometric determination of zinc in blood serum of diabetic patients using bis-[2,6-(2´-hydroxy-4´-sulpho-1´-napthylazo)]pyridine disodium salt

Bis-[2,6-(2´-hydroxy-4´-sulpho-1´-napthylazo)]pyridine disodium salt (HSNP), a new heterocyclic azo dye is proposed as a sensitive spectrophotometric reagent for zinc. A selective spectrophotometric method is presented for the trace determination of zinc in blood serum using HSNP as spectrophotometric reagent (λmax = 565 nm) in basic aqueous solution (pH range = 7.5 to 9.1). The HSNP forms a 1:1 purple coloured complex. The Sandell’s Sensitivity is 1.37× 10-3 dm3 mol-1 cm-2 with molar absorptivity 4.6 ×104 mol L-1 cm-1. The proposed method has been successfully applied to the determination of zinc in blood samples of diabetic patients. The precision and the accuracy obtained were satisfactory.

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Photodegradation of 2,4,6 trinitrotoluene, nitrobenzene mixtures in TIO2 suspension

The photo catalytic oxidation of nitrobenzene, 2, 4,6-trinitrotoluene in aqueous suspensions of titanium dioxide (TiO2 Degussa type P25 was investigated. Under oxygen conditions, irradiation with the Pyrex-filtered out put of 15 W high pressure mercury-arc lamp resulted in complete (more 90 %) mineralization of 50 ppm of TNT, 30 ppm of NB within few hours. At the beginning irradiation, reduction by conduction band electrons may play a more significant role in the photo catalytic degradation of the studied mixtures. The resulted in aromatic ammine compounds were more easily to be oxidized by the hydroxyl radicals.

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A study on polypropylene fabric using ion irradiation

The main goal of this work was examination of structural and compositional changes in the Polypropylene (PP) fabrics caused by ion irradiation. In this work, the PP fabric were irradiated with CO2 ions. The Implantation conditions (i.e, exposure time, beam current, and discharge power) were changed to control the extend of surface modification and the effects of irradiation were studied using different instruments. Also dye ability of the untreated sample and treated under different conditions were investigated by using a 3% wt aqueous solution of a basic dyestuff.

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Corrosion inhibitive properties of different plant extract

The natural products in acidic media were tested for corrosion inhibition of Cu, Al and Mild-Steel in 0.5N HCl acid solution at 30 to 40 0C temperature range by Weight Loss technique, it reveals that Natural Products works as a corrosion inhibitor in halide media and protect the metals from the corrosion with great efficiency.

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Evaluation of activities of Solanum nigrum fruit extract

The present study was designed to evaluate the analgesic, anti-inflammatory and antimicrobial activities of ethanolic extract of fruits of Solanum nigrum plant blonging to Solanaceae family. The anti-inflammatory activity of the extract was evaluated by using Carrageenan-induced rat paw edema while analgesic activity of the extract was evaluated for its central and peripheral pharmacological actions by using Eddy’s hot plate and acetic acid induced writhing respectively. The study was carried out using doses of 100, 250 & 500 mg/kg orally. The extract showed showed significant analgesic and anti-inflammatory activity at the dose of 500 mg/kg (P<0.01) as compare to standard drug Diclofenac sodium (50 mg/kg). The plant extract significantly inhibited the S. aureus and B. sublitis (Gram +ve) at all the tested concentrations (100, 75, 50 and 25mg/ml) as compare to standard drug Ciprofloxacin (20 µg/ml) whereas the extract failed to show inhibitory effect against E. coli and P. aeruginosa (Gram –ve) at a concentration of 25mg/ml. The extract also showed significant inhibitory effect against C. albicans at all concentrations except at 25 mg/ml as compare to standard drug Amphotericin B (100 µg /ml).

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Persistent band heads of second positive system of N2 and first negative system of N2+ in the spectra of lightning

The spectra of cloud to ground lightning flash data have been analyzed for the three year period 2005-2008, for a geographical area centered on Dibrugarh (27o.29/ N, 94o.58/ E), Assam, India. Of the fifty spectra recorded on a Quartz spectrograph thirty exhibited only continuum. The remaining spectra indicated the clear presence of the persistent band heads of the second positive band system of molecular nitrogen. The spectra of lightning with reference to the (0,0) bands of the 2nd positive system of nitrogen has been recorded for the first time with the help of a conventional Q-24 medium quartz spectrograph. It would follow that molecular nitrogen is the predominate species which reveals itself as a persistent band heads belonging to the 2nd positive system. The (0,0) band of the second positive system is observed in most of the spectra, but with different intensities. In some cases the first negative system of singly ionized molecular nitrogen (N2+) is also observed. It is evident that the spectra photographed with lightning furnish information of great value in regard to the identification of the material present in the atmosphere.

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Design and fabrication of a DC cylindrical magnetron sputtering device

A dc cylindrical magnetron sputtering device is designed and its characteristics are studied. The device consists of two copper cylinders with 1.5 and 5 cm in radius and 20 cm in length. A magnetic coil mounted around the outer cylinder generates an axial magnetic field up to 550 G. The effect of different magnetic field on the ionization rate of the discharge is observed. It is shown that the electrical behavior of the discharge strongly depends on the values of the magnetic field and shows an optimum value at which the power absorbed by the plasma is maximum. The effect of different pressure on the ionization rate is also studied and the results are reported.

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Antioxidant activity and hepatoprotective potential of Terminalia pallida

Terminalia pallida (TP)Brandis is one of the oldest medicinal herb of India, is an ingredient of Indian Ayurvedic drug 'triphala' used for the treatment of digestion and liver disorders. In Indian traditional system of medicine, the fruits are also used in the treatment of hepatic disorders and treatment of diabetes by tribal people. Acetaminophen (APAP) is used as an analgesic which produces liver and kidney necrosis in mammals at high doses. The aim of the present study was to investigate the hepatoprotective and antioxidant activities of the ethanol extract of Terminalia pallida at two doses level of 250 mg/kg & 500 mg/kg B/W on acetaminophen- induced hepatotoxicity in rats. The results of study showed that APAP significantly increased serum levels of GOT & GPT, ALP and total bilirubin. In addition, the ethanol extract of TP significantly (p<0.01) elevated the decreased level of antioxidant enzymes such as superoxide dismutase (SOD) & catalase (CAT), glutathione peroxidase (GPX), glutathione-s-transferase (GST) and reduced glutathione (GSH). Histological analysis of the liver of these rats revealed marked necro-inflammatory changes by APAP and ethanol extract of TP attenuated the necro-inflammatory changes in the liver. The activity of ethanol extract of Terminalia pallida at 500 mg/kg B/W was comparable to the standard drug silymarin (25mg/kg B/W). This study reveals that ethanol extract of TP showed significant hepatoprotective and antioxidant properties from APAP induced liver damage & oxidative stress.

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Prediction of biochemical properties of protein active site residues with ANN classifier

In this study, we present a method for the prediction of physiochemical properties of catalytic sites residues using a suitable Artificial Neural Networking (ANN) Feed Forward Backpropagation algorithm coupled with a set of structural proteins with the properties of their amino acid residues. The method has been applied to a set of 100 structural proteins from the Protein Data Bank (PDB) having a ligand at their active site. Using Ligplot program for searching of active site residues and Surface racer for identifying the non active site moieties, the identified amino acid residues were classified in 15 different categories based on their physiochemical properties. After classification of active and non active site amino acids, their properties were converted into machine language. Furthermore, we created Neural Network Using Matlab software and generated algorithm for training and testing of data. Thereafter, analysis of results showed that 95% of active site’s physiochemical properties were correctly predicted. It is hoped that this work would help in determining the surface topographic properties for ligand binding sites residues in protein. The computational outcome would be helpful in ligand designing, molecular docking, de novo drug designing and structural identification and functional sites Comparisons.

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http://scholarsresearchlibrary.com/AASR-first-issue/aasr-first-issue-8-17.html

The oxidation of 2,4.6- trinitroresorcine (TNR) using zero-valent iron (ZVI)

This paper describes the character of the reduction of TNR by ZVI in anaerobic conditions and the oxidative reaction of amine resorcine in the system of ZVI-EDTA-O2. The products of TNR by ZVI in anaerobic conditions were amine resorcine compounds. These compounds tend to be easier to be oxidized by the free radical OH generated in the system of ZVI-EDTA-O2. HPLC method and analysis COD have been used for monitoring efficiency of reactions. The experiments have suggested that the removal of TNR from groundwater is likely implemented by two steps. The first step is reduction of TNR bys ZVI to form amine resorcine. The second step is oxidation of amine resorcine in system consisting of ZVI-EDTA-O2.From the obtained results a model for TNR contaminated groundwater treatment has been suggested.

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